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1

Regulation of mammary morphogenesis: Evidence for extracellular matrix-mediated inhibition of ductal budding by transforming growth factor-β1

Gary B. Silberstein, Kathleen C. Flanders, Anita B. Roberts, Charles W. Daniel

Journal:

Developmental Biology

Year:

1992

Language:

english

File:

PDF, 27.55 MB

english, 1992

2

Localization and binding of transforming growth factor-β isoforms in mouse preimplantation embryos and in delayed and activated blastocysts

B.C. Paria, Kelly L. Jones, Kathleen C. Flanders, S.K. Dey

Journal:

Developmental Biology

Year:

1992

Language:

english

File:

PDF, 11.76 MB

english, 1992

3

Expression of transforming growth factor-βs 1–4 in chicken embryo chondrocytes and myocytes

Sonia B. Jakowlew, Pamela J. Dillard, Thomas S. Winokur, Kathleen C. Flanders, Michael B. Sporn, Anita B. Roberts

Journal:

Developmental Biology

Year:

1991

Language:

english

File:

PDF, 33.66 MB

english, 1991

4

Altered expression of transforming growth factor-β1 in cervical neoplasia as an early biomarker in carcinogenesis of the uterine cervix

John T. Comerci Jr., Carolyn D. Runowicz, Kathleen C. Flanders, Carol De Victoria, Abbie L. Fields, Anna S. Kadish, Gary L. Goldberg

Journal:

Year:

1996

Language:

english

File:

PDF, 986 KB

english, 1996

5

Expression, localization, and function of transforming growth factor-βs in embryonic chick spinal cord, hindbrain, and dorsal root ganglia

Klaus Unsicker, Carola Meier, Kerstin Krieglstein, Birgit M. Sartor, Kathleen C. Flanders

Journal:

Developmental Neurobiology

Year:

1996

Language:

english

File:

PDF, 1.54 MB

english, 1996

6

Transgenic models for the study of prostate cancer

Timothy C. Thompson, Luan D. Truong, Terry L. Timme, Dov Kadmon, Bryan K. McCune, Kathleen C. Flanders, Peter T. Scardino, Sang Hee Park

Journal:

Year:

1993

Language:

english

File:

PDF, 811 KB

english, 1993

7

Immunohistochemical expression of smads 1–6 in the 15-day gestation mouse embryo: signaling by BMPs and TGF-βs

Kathleen C. Flanders, Edward S. Kim, Anita B. Roberts

Journal:

Developmental Dynamics

Year:

2001

Language:

english

File:

PDF, 1.35 MB

english, 2001

8

Transforming growth factor β1 as a biomarker for prostate cancer

Timothy C. Thompson, Luan D. Truong, Terry L. Timme, Dov Kadmon, Bryan K. McCune, Kathleen C. Flanders, Peter T. Scardino, Sang Hee Park

Journal:

Journal of Cellular Biochemistry

Year:

1992

Language:

english

File:

PDF, 851 KB

english, 1992

9

Immunodetection and quantitation of the two forms of transforming growth factor-beta (TGF-β1 and TGF-β2) secreted by cells in culture

David Danielpour, Linda L. Dart, Kathleen C. Flanders, Anita B. Roberts, Michael B. Sporn

Journal:

Journal of Cellular Physiology

Year:

1989

Language:

english

File:

PDF, 861 KB

english, 1989

10

Inhibition of the chondrocyte phenotype by retinoic acid involves upregulation of metalloprotease genes independent of TGF-β

Dr. R. Tracy Ballock, Ahlke Heydemann, Lalage M. Wakefield, Kathleen C. Flanders, Anita B. Roberts, Michael B. Sporn

Journal:

Journal of Cellular Physiology

Year:

1994

Language:

english

File:

PDF, 839 KB

english, 1994

11

Effectiveness of ceftriaxone plus doxycycline in the treatment of patients hospitalized with community-acquired pneumonia

Scott A. Flanders, Vicky Dudas, Kathleen Kerr, Charles E. McCulloch, Ralph Gonzales

Journal:

Journal of Hospital Medicine

Year:

2006

Language:

english

File:

PDF, 78 KB

english, 2006

12

Transforming growth factor-β1 expression in early biopsy specimen predicts long-term graft function following pediatric renal transplantation

Takeshi Ishimura, Masato Fujisawa, Shuji Isotani, Akihiro Higuchi, Kazumoto Iijima, Soichi Arakawa, Katharina Hohenfellner, Kathleen C Flanders, Norishige Yoshikawa, Sadao Kamidono

Journal:

Clinical Transplantation

Year:

2001

Language:

english

File:

PDF, 4.91 MB

english, 2001

13

Role of Smad3 in the hormonal modulation of in vivo wound healing responses

Gillian S. Ashcroft, Stuart J. Mills, Kathleen C. Flanders, Lyudmila A. Lyakh, Mario A. Anzano, Stephen C. Gilliver, Anita B. Roberts

Journal:

Wound Repair and Regeneration

Year:

2003

Language:

english

File:

PDF, 162 KB

english, 2003

14

The effects of retinoid status on TGF β expression during mouse embryogenesis

Radma Mahmood, Kathleen C. Flanders, Gillian M. Morriss-Kay

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Year:

1995

Language:

english

File:

PDF, 7.39 MB

english, 1995

15

Expression of transforming growth factor-β isoforms in the rat male accessory sex organs and epididymis

Kartiki V. Desai, Kathleen C. Flanders, P. Kondaiah

Journal:

Cell and Tissue Research

Year:

1998

Language:

english

File:

PDF, 1.36 MB

english, 1998

16

Expression of TGF-β signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics

Jonine D. Figueroa, Kathleen C. Flanders, Montserrat Garcia-Closas, William F. Anderson, Xiaohong R. Yang, Rayna K. Matsuno, Máire A. Duggan, Ruth M. Pfeiffer, Akira Ooshima, Robert Cornelison, Gretch

Journal:

Breast Cancer Research and Treatment

Year:

2010

Language:

english

File:

PDF, 303 KB

english, 2010

17

Transforming Growth Factor-βs and Mammary Gland Involution; Functional Roles and Implications for Cancer Progression

Kathleen C. Flanders, Lalage M. Wakefield

Journal:

Journal of Mammary Gland Biology and Neoplasia

Year:

2009

Language:

english

File:

PDF, 367 KB

english, 2009

18

Smad3 as a mediator of the fibrotic response

Kathleen C. Flanders

Journal:

International Journal of Experimental Pathology

Year:

2004

Language:

english

File:

PDF, 4.97 MB

english, 2004

19

Smad-3 as a mediator of the fibrotic response

Kathleen Flanders, Misako Sato, Akira Ooshima, Angelo Russo, Anita Roberts

Journal:

International Journal of Experimental Pathology

Year:

2004

Language:

english

File:

PDF, 372 KB

english, 2004

20

TGF-β Rescues Target-deprived Preganglionic Sympathetic Neurons in the Spinal Cord

Dieter Blottner, Nicole Wolf, Astrid Lachmund, Kathleen C. Flanders, Klaus Unsicker

Journal:

European Journal of Neuroscience

Year:

1996

Language:

english

File:

PDF, 4.93 MB

english, 1996

21

Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine-induced hepatic fibrosis in mice

Giovanni Latella, Antonella Vetuschi, Roberta Sferra, Valentina Catitti, Angela D'Angelo, Giuliana Zanninelli, Kathleen C. Flanders, Eugenio Gaudio

Journal:

Liver International

Year:

2009

Language:

english

File:

PDF, 2.49 MB

english, 2009

22

Smad3: A Key Player in Pathogenetic Mechanisms Dependent on TGF-β

ANITA B. ROBERTS, ANGELO RUSSO, ANGELINA FELICI, KATHLEEN C. FLANDERS

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 3.30 MB

2003

23

Conditional overexpression of TGF-β1 disrupts mouse salivary gland development and function

Hall, Bradford E, Zheng, Changyu, Swaim, William D, Cho, Andrew, Nagineni, Chandrasekharam N, Eckhaus, Michael A, Flanders, Kathleen C, Ambudkar, Indu S, Baum, Bruce J, Kulkarni, Ashok B

Journal:

Laboratory Investigation

Year:

2010

Language:

english

File:

PDF, 962 KB

english, 2010

24

Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice

Saika, Shizuya, Kono-Saika, Satoko, Tanaka, Takeshi, Yamanaka, Osamu, Ohnishi, Yoshitaka, Sato, Misako, Muragaki, Yasuteru, Ooshima, Akira, Yoo, Jiyun, Flanders, Kathleen C

Journal:

Laboratory Investigation

Year:

2004

Language:

english

File:

PDF, 753 KB

english, 2004

25

Therapeutic effects of adenoviral gene transfer of bone morphogenic protein-7 on a corneal alkali injury model in mice

Saika, Shizuya, Ikeda, Kazuo, Yamanaka, Osamu, Flanders, Kathleen C, Nakajima, Yuji, Miyamoto, Takeshi, Ohnishi, Yoshitaka, Kao, Winston W-Y, Muragaki, Yasuteru, Ooshima, Akira

Journal:

Laboratory Investigation

Year:

2005

Language:

english

File:

PDF, 784 KB

english, 2005

26

Inhibition of p38MAP kinase suppresses fibrotic reaction of retinal pigment epithelial cells

Saika, Shizuya, Yamanaka, Osamu, Ikeda, Kazuo, Kim-Mitsuyama, Shokei, Flanders, Kathleen C, Yoo, Jiyun, Roberts, Anita B, Nishikawa-Ishida, Iku, Ohnishi, Yoshitaka, Muragaki, Yasuteru

Journal:

Laboratory Investigation

Year:

2005

Language:

english

File:

PDF, 832 KB

english, 2005

27

Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium

Saika, Shizuya, Shirai, Kumi, Yamanaka, Osamu, Miyazaki, Ken-ichi, Okada, Yuka, Kitano, Ai, Flanders, Kathleen C, Kon, Shigeyuki, Uede, Toshimitsu, Kao, Winston Whei-Yang

Journal:

Laboratory Investigation

Year:

2007

Language:

english

File:

PDF, 542 KB

english, 2007

28

Transforming growth factor-beta — mediator of carcinogenesis, inflammation and embryonic development

Kathleen C. Flanders, Ursula I. Heine, Nancy L. Thompson, Lalage M. Wakefield, Michael B. Sporn, Anita B. Roberts

Journal:

Analytical and Bioanalytical Chemistry

Year:

1988

Language:

english

File:

PDF, 145 KB

english, 1988

29

Transforming growth factors-β protect primary rat hippocampal neuronal cultures from degeneration induced by β-amyloid peptide

Renée Feng Ren, Kathleen Corey Flanders

Journal:

Year:

1996

File:

PDF, 1.45 MB

1996

30

Analogous tamoxifen and estrogen effects on transforming growth factor-betas 1 and 2 in the rat uterus

Belinda M. Sartor, Oliver Sartor, Kathleen C. Flanders

Journal:

Reproductive Toxicology

Year:

1995

Language:

english

File:

PDF, 979 KB

english, 1995

31

Molecular control of neural plasticity by the multifunctional growth factor families of the FGFs and TGF-βs

Klaus Unsicker, Sibille Engels, Carmen Hamm, Gerson Lüdecke, Carola Meier, Jochen Renzing, Hans Georg Terbrack, Kathleen Flanders

Journal:

Annals of Anatomy - Anatomischer Anzeiger

Year:

1992

Language:

english

File:

PDF, 2.85 MB

english, 1992

32

ENDOCRINE EXPRESSION OF THE ACTIVE FORM OF TGF-β1 IN THE TGF-β1 NULL MICE FAILS TO AMELIORATE LETHAL PHENOTYPE

Glenn Longenecker, Tamizchelvi Thyagarajan, Chandrasekharam N. Nagineni, Kathleen C. Flanders, Valentina Factor, Georgina Miller, Jerrold M. Ward, Aysegul Nalca, Vivek M. Rangnekar, Snorri Thorgeirsso

Journal:

Year:

2002

Language:

english

File:

PDF, 1.25 MB

english, 2002

33

TGF-β1 Prevents Hypertrophy of Epiphyseal Chondrocytes: Regulation of Gene Expression for Cartilage Matrix Proteins and Metalloproteases

R.Tracy Ballock, Ahlke Heydemann, Lalage M. Wakefield, Kathleen C. Flanders, Anita B. Roberts, Michael B. Sporn

Journal:

Developmental Biology

Year:

1993

File:

PDF, 2.01 MB

1993

34

Transforming Growth Factor Beta 2 is the Predominant Isoform in the Neural Retina, Retinal Pigment Epithelium-Choroid and Vitreous of the Monkey Eye

Bruce A. Pfeffer, Kathleen C. Flanders, Christopher J. Guérin, David Danielpour, Don H. Anderson

Journal:

Experimental Eye Research

Year:

1994

File:

PDF, 1.06 MB

1994

35

Transforming Growth Factor-βs Block Cytokine Induction of Catalase and Xanthine Oxidase mRNA Levels in Cultured Rat Cardiac Cells

Kathleen C. Flanders, Anita R. Bhandiwad, Thomas S. Winokur

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1997

Language:

english

File:

PDF, 541 KB

english, 1997

36

Inducible Nitric Oxide Production and Expression of Transforming Growth Factor-β1 in Serum and CSF after Cerebral Ischaemic Stroke in Man

Jerzy Krupinski, Yoram Vodovotz, Cheng-gang Li, Agnieszka Slowik, Dory Beevers, Kathleen C. Flanders, Greg Lip, Pat Kumar, Andrzej Szczudlik

Journal:

Year:

1998

Language:

english

File:

PDF, 313 KB

english, 1998

37

Semisynthetic d-His1,Nϵ-acetimidoglucagon: Structure-function relationships

Alan M. Mahrenholz, Kathleen C. Flanders, Naseema M. Hoosein, Frank R.N. Gurd, Ruth S. Gurd

Journal:

Archives of Biochemistry and Biophysics

Year:

1987

Language:

english

File:

PDF, 700 KB

english, 1987

38

Transforming growth factor β1 is an epithelial-derived signal peptide that influences otic capsule formation

Dorothy A. Frenz, Vera Galinovic-Schwartz, Wei Liu, Kathleen C. Flanders, Thomas R. Van de Water

Journal:

Developmental Biology

Year:

1992

Language:

english

File:

PDF, 37.66 MB

english, 1992

39

Autoinduction of mRNA and protein expression for transforming growth factor-βs in cultured cardiac cells

Kathleen C. Flanders, Michael G. Holder, Thomas S. Winokur

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1995

Language:

english

File:

PDF, 1.23 MB

english, 1995

40

TRPV1 Involvement in Inflammatory Tissue Fibrosis in Mice

Yuka Okada, Peter S. Reinach, Kumi Shirai, Ai Kitano, Winston W.-Y. Kao, Kathleen C. Flanders, Masayasu Miyajima, Hongshan Liu, Jianhua Zhang, Shizuya Saika

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.47 MB

english, 2011

41

Smad3 is key to TGF-β-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis

Anita B. Roberts, Fang Tian, Stacey DaCosta Byfield, Christina Stuelten, Akira Ooshima, Shizuya Saika, Kathleen C. Flanders

Journal:

Cytokine & Growth Factor Reviews

Year:

2006

Language:

english

File:

PDF, 325 KB

english, 2006

42

Hunting with lead: Association between blood lead levels and wild game consumption

Shahed Iqbal, Wendy Blumenthal, Chinaro Kennedy, Fuyuen Y. Yip, Stephen Pickard, W. Dana Flanders, Kelly Loringer, Kirby Kruger, Kathleen L. Caldwell, Mary Jean Brown

Journal:

Environmental Research

Year:

2009

Language:

english

File:

PDF, 207 KB

english, 2009

43

Expression of Smad7 in Mouse Eyes Accelerates Healing of Corneal Tissue after Exposure to Alkali

Shizuya Saika, Kazuo Ikeda, Osamu Yamanaka, Takeshi Miyamoto, Yoshitaka Ohnishi, Misako Sato, Yasuteru Muragaki, Akira Ooshima, Yuji Nakajima, Winston W.-Y. Kao, Kathleen C. Flanders, Anita B. Roberts

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 2.50 MB

english, 2005

44

Therapeutic Effect of Topical Administration of SN50, an Inhibitor of Nuclear Factor-κB, in Treatment of Corneal Alkali Burns in Mice

Shizuya Saika, Takeshi Miyamoto, Osamu Yamanaka, Tadashi Kato, Yoshitaka Ohnishi, Kathleen C. Flanders, Kazuo Ikeda, Yuji Nakajima, Winston W.-Y. Kao, Misako Sato, Yasuteru Muragaki, Akira Ooshima

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 1.25 MB

english, 2005

45

Smad3 Signaling Is Required for Epithelial-Mesenchymal Transition of Lens Epithelium after Injury

Shizuya Saika, Satoko Kono-Saika, Yoshitaka Ohnishi, Misako Sato, Yasuteru Muragaki, Akira Ooshima, Kathleen C. Flanders, Jiyun Yoo, Mario Anzano, Chia-Yang Liu, Winston W.–Y. Kao, Anita B. Roberts

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 2.56 MB

english, 2004

46

Interference with Transforming Growth Factor-β/ Smad3 Signaling Results in Accelerated Healing of Wounds in Previously Irradiated Skin

Kathleen C. Flanders, Christopher D. Major, Alidad Arabshahi, Ekinadese E. Aburime, Miya H. Okada, Makiko Fujii, Timothy D. Blalock, Gregory S. Schultz, Anastasia Sowers, Mario A. Anzano, James B. Mit

Journal:

The American Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 1.70 MB

english, 2003

47

Mice Lacking Smad3 Are Protected Against Cutaneous Injury Induced by Ionizing Radiation

Kathleen C. Flanders, Catherine D. Sullivan, Makiko Fujii, Anastasia Sowers, Mario A. Anzano, Alidad Arabshahi, Christopher Major, Chuxia Deng, Angelo Russo, James B. Mitchell, Anita B. Roberts

Journal:

The American Journal of Pathology

Year:

2002

Language:

english

File:

PDF, 4.84 MB

english, 2002

48

Kainate treatment alters TGF-β3 gene expression in the rat hippocampus

Hyoung-Chun Kim, Guoying Bing, Seong-Jin Kim, Wang-Kee Jhoo, Eun-Joo Shin, Myung Bok Wie, Kwang Ho Ko, Won-Ki Kim, Kathleen C Flanders, Shin-Geon Choi, Jau-Shyong Hong

Journal:

Molecular Brain Research

Year:

2002

Language:

english

File:

PDF, 964 KB

english, 2002

49

Transforming growth factor-β protects human hNT cells from degeneration induced by β-amyloid peptide: involvement of the TGF-β type II receptor

Renée Feng Ren, David B Hawver, Richard S Kim, Kathleen Corey Flanders

Journal:

Molecular Brain Research

Year:

1997

Language:

english

File:

PDF, 538 KB

english, 1997

50

Transforming growth factor-β inhibits apoptosis induced by β-amyloid peptide fragment 25–35 in cultured neuronal cells

Edward S Kim, Richard S Kim, Reneé Feng Ren, David B Hawver, Kathleen Corey Flanders

Journal:

Molecular Brain Research

Year:

1998

Language:

english

File:

PDF, 344 KB

english, 1998